Nogent-sur-Vernisson (French pronunciation: [nɔʒɑ̃ syʁ vɛʁnisɔ̃]) is a commune in the eastern part of the Loiret department in the Centre-Val de Loire region central-north France.

The main employer in the town is the CIMRG plant which manufactures components for Renault cars and employs some 800 people.

Nogent-sur-Vernisson station has rail connections to Montargis, Nevers and Paris.

Nogent-sur-Vernisson is the site of the Arboretum national des Barres, adjacent to which is a division of the research agency Irstea (formerly Cemagref), which works to conserve the genetic resources of native trees.

[4] The town has a 12th-century AD church of St Martin in which Pope Pius VII celebrated Mass while on his way to the coronation of Napoleon Bonaparte in 1804.