Nomexy (French pronunciation: [nɔmsi] ⓘ) is a commune in the Vosges department in Grand Est in northeastern France.

The canal remains popular with leisure and recreational users, though the transport of merchandise for which it was constructed during the nineteenth century has been taken over by the Route Nationale RN57 which during the closing years of the twentieth century was upgraded to quasi-autoroute quality from Nancy in the north to Remiremont en route to the Bussang Pass and Mulhouse to the south-east.

There is also a considerable level of commuting to one or other of the many industrial zones on the edges of the small towns that are strung along the Moselle in the Épinal region.

Nevertheless, between 1968 and 2006 the population of Nomexy declined by more than 20%, which is part of a larger pattern of migration from the villages to the cities that characterised France as industrialisation accelerated during the second half of the twentieth century.

Neighbouring communes are Portieux to the north, Châtel-sur-Moselle in the east, Vaxoncourt to the south-east, Igney in the south, Frizon to the south-west and Vincey in the West.