She was created by Paul Dini and Bruce Timm for Batman: The Animated Series, in which she is depicted as the terminally ill wife of Dr. Victor Fries, who cryogenically freezes her and becomes the supervillain Mr.
Nora is later adapted into the mainstream comic book canon and revived as a supervillain under the aliases Lazara and Mrs.
Freeze: SubZero, Victor retrieved Nora's chamber and brought it to an Arctic cave until a submarine crew accidentally damages it.
Victor murders the crew before bribing an old colleague into helping him kidnap Barbara Gordon as she shares Nora's rare blood type.
In The New Batman Adventures episode "Cold Comfort", Nora is said to have waited for the presumed dead Victor for some time before eventually marrying her doctor Francis D'Anjou.
This subplot is expanded upon in volume two of The Batman Adventures tie-in comic series, in which D'Anjou stages his abduction and death to frame Victor and make Nora hate him.
[1][2][3] In The New 52 continuity reboot, Nora is not romantically involved with Victor, who attempts to cure her heart disease and falls in love with her.