[4][2] Kirkpatrick was a founding member and accordion player for the Grammy Award winning and platinum record selling band Edward Sharpe and the Magnetic Zeros.

After seven years touring on the road she turned her focus to writing and directing, selling series to CBS, Hulu and Comedy Central among others.

[5] In 2020, Kirkpatrick became a writer on two Amazon series: Daisy Jones & the Six, produced by Reese Witherspoon, and Rodeo Queens starring Dakota Johnson.

[9] In a 2017 Forbes article, Kirkpatrick mentions virtual reality's ability to cause "spatial un-comfortability," and her aim to make the viewer the lead character of the story.

She has played many other roles in film and TV, including Men at Work, Jennifer Falls, Don't Trust the B, and Chasing Life.