The eastern wing of the General Office Building–South was constructed in 1896 on the site of the prior N&W headquarters building that had been destroyed in a fire in January of the same year.

GOB–North's Art Deco architecture utilizes similar design elements to New York City's Chrysler Building.

[4] The Passenger Station is located just east of GOB–South and downhill from the Hotel Roanoke (which was also constructed and owned by N&W).

[5] The two wings comprising GOB–South were converted to upscale apartments in 2002,[5] while GOB–North is the home of the Roanoke Higher Education Center.

[7] As of 2023[update] it houses the city's visitor center, the Historical Society of Western Virginia, and the O. Winston Link Museum.