The 21.5 kilometres (13.4 mi) expressway is expected to cost about S$7.47 billion[1] when fully completed in 2029 as North-South Corridor and will connect the East Coast Parkway (ECP) with the northern parts of Singapore.

[2] The NSC will have a total of 16 entrances and 17 exits to connect towns along the north-south corridor—Woodlands, Sembawang, Yishun, Ang Mo Kio, Bishan and Toa Payoh—with the city centre.

[5][6] Additionally, the surface streets that run along the underground tunnel of the NSC will see road lanes reprioritised for walking, cycling, public transport and community spaces.

[17] In August 2016, several units in the Ellison Building which was built in 1924, was considered for partial demolition and reconstruction after the completion of the NSC, despite its previous conservation gazette in 2008 by the URA.

[22][23] In April 2021, another four-storey building along Thomson Road, comprising 12 residential units and 4 shops, was acquired to make way for construction of the NSC.

[13] This sparked some unhappiness with the unit owners who were looking forward to a collective sale on the open market, since the proceeds were expected to be higher than the compensation that they would have received from the land acquisition.

[29] On 17 September 2023, an accident occurred resulting in the death of a 41-year-old construction worker at the worksite of Cavenagh Road when a pallet of gas cylinders toppled.