From 1526 to 1527, the area was ruled by the independent Serb ruler, emperor Jovan Nenad, while during Ottoman administration (16th-17th century), it was part of the Sanjak of Segedin.

Since the abolishment of the Theiß-Marosch section of the Military Frontier in 1751, part of that territory was also included into the Batsch-Bodrog County.

During the royal Serb-Croat-Slovene (Yugoslav) administration (1918-1941), the area was part of the Novi Sad County (1918-1922), Bačka Oblast (1922-1929), and Danube Banovina (1929-1941).

The most remarkable religious buildings are Subotica Synagogue, Cathedral of Saint Teresa of Avila from 1797, a Franciscan Monastery from 1736, and St Dimitrije Serbian Orthodox Church in Aleksandrovo neighborhood from 1818.

Subotica ranks among the leading communities in Serbia when it comes to crop yields (maize, wheat and sunflower).