Old Main — the centerpiece of the NDSCS campus for generations — has been listed on the National Register of Historic Places since 1984.

Designed by architect John M. Coxhead, Old Main was built in 1891 as the original home of Red River Valley University.

Located across from the Fargodome on 19th Avenue North in Fargo, NDSCS-Fargo serves as the home to academic programming and non-credit training.

NDSCS offers academic options in the following career clusters: The North Dakota State College of Science's sports teams are known as the Wildcats.

The NDSCS Wildcats are members of the National Junior College Athletic Association (NJCAA).