It enrolls around 1,200 students and serves six rural counties in North Florida: Madison, Hamilton, Lafayette, Jefferson, Suwannee, and Taylor.

The school was founded as North Florida Junior College in 1957, with classes beginning the following year.

In July 1995, the District Board of Trustees changed the institution's name to North Florida Community College.

Following the passage of the Civil Rights Act of 1964, which buttressed the 1954 Brown v. Board of Education court decision prohibiting racial discrimination in schools, Suwannee River Junior College was closed.

[1] In July 1995, the District Board of Trustees changed the institution's name to North Florida Community College.