Its boundaries are Main Street (west), Redwood Avenue (north), the Red River (east), and the Canadian Pacific Railway mainline (south), which bisects the peninsula.
As the Red River Colony (as the Winnipeg region was known) grew, a small cluster of commercial establishments developed on the Fort Garry road at Point Douglas by 1862, notably those of William Fonseca and Edmond Barber.
Among the houses of these men, there developed more modest cottages, industry such as Brown and Rutherford, a lumber company established in Point Douglas in 1872.
With the railroad completed by 1885, Winnipeg experienced an intense period of growth, and by 1914, Point Douglas had become a densely populated working-class neighbourhood, with many immigrants from Eastern Europe.
North Point Douglas continues to be primarily a residential neighbourhood but is also home to commercial and light industrial uses, with industry located mainly on the south side of the neighbourhood along the CPR tracks and commercial establishments on the western side, along Main Street, one of the city's busiest thoroughfares.
It has faced many of the same challenges that have characterized the North American city in the postwar decades: population and economic decline, crime, drug abuse, and a lack of investment.