North Third Street Historic District is a national historic district located at Louisiana, Pike County, Missouri.

Located in the district are the separately listed Louisiana Public Library and Luce-Dyer House.

Other notable buildings include the William C. Hardin House (c. 1843), James H. Johnson House (c. 1861), Edward G. McQuie House (c. 1858), St. Joseph's Catholic Church (1874), and Frank Boehm, Jr.

[2] It was listed on the National Register of Historic Places in 2005.

This article about a property in Pike County, Missouri on the National Register of Historic Places is a stub.