It is served by the Bakerloo line of the London Underground and the Lioness line of the London Overground, between South Kenton and Wembley Central stations.

The station is located on the south side of East Lane, part of the London Borough of Brent, serving residents of North Wembley and western parts of Wembley Park.

The station was first opened by the London and North Western Railway on 15 June 1912 as part of the New Line between Euston and Watford Junction; LER Bakerloo line services began on 16 April 1917.

Originally to be called East Lane, after the road passing over the railway at this location, it was named North Wembley from opening.

It was built to the same general design as the other new stations on the same line and the layout at North Wembley station makes it almost identical to Kenton two stops to the north.