The section of E. Northern Pkwy from Harford Road to Fleetwood Ave was originally called German Lane.

[1] Northern Parkway starts at an at-grade intersection with Liberty Heights Avenue (MD 26) in Northwest Baltimore near the community of Lochearn.

The road heads northeast as a six lane divided boulevard, passing through some residential areas before meeting Wabash Avenue.

After its intersections with Roland Avenue and Charles Street (MD 139), Northern Parkway temporarily reduces to a four-lane undivided road.

Between 1950 and 1976, parts of Northern Parkway were expanded to six lanes with a median from Bellona Avenue east.

The Rogers Avenue Metro Subway Station is located near Northern Parkway, and the Mt.

Route M-8 ran along Northern Parkway from Wabash Avenue to Liberty Road until it was rerouted in 2005.