It is the leading subsidiary of Northwest Bancshares, Inc., a bank holding company, and operates 170 branches in central and Western Pennsylvania, Western New York, Northeast Ohio, Appalachian Ohio, and Indiana.

[2] In 1985, the bank acquired four southwestern Pennsylvania branches from Equimark, a subsidiary of Pittsburgh-based Equibank.

[2] It also changed its regulatory agency to the FDIC and became a mutual savings bank.

[8] The transaction expanded Northwest's presence in Indiana, and grew the bank's number of branches to 221 across four states.

In February 2021, the bank remains in Warren, Pennsylvania, however the bank moved its holding company headquarters from Warren, Pennsylvania to Columbus, Ohio, relocating several key executives, including Ron Seiffert, the company's chief executive officer.