One hundred students enrolled at the new school, which was initially located in a 19th-century mansion in Alma, Michigan.

[6] During the same time frame during which the Indiana campus was opened, a Northwood facility was also established in Texas.

A joint program with the Hotel Institute Montreux was established in 2001 to combine Swiss hospitality traditions with American management practices.

Its most popular undergraduate majors, based on 2021 graduates (including by distance learning), were:[10] The athletic teams of Northwood University's Michigan (main) campus are called the Timberwolves.

The campus is a member of the NCAA Division II ranks, primarily competing in the Great Midwest Athletic Conference (G-MAC) since the 2022–23 academic year.

The campus was located in West Palm Beach, Florida, and was a member of the National Association of Intercollegiate Athletics (NAIA); primarily competing in the Sun Conference (formerly known as the Florida Sun Conference (FSC) until after the 2007–08 school year) from 1994–95 to 2014–15.