Nossen (German pronunciation: [ˈnɔsn̩] ⓘ; Upper Sorbian: Nosyn, pronounced [ˈnɔsɨn]) is a town in the district of Meissen, in Saxony, Germany.

The town is dominated by a large Renaissance castle.

Nossen is best known for its proximity to a motorway junction where the A14 merges onto the A4.

Nearest towns are Roßwein, Großschirma, Reinsberg and Striegistal in Mittelsachsen districts and Käbschütztal, Lommatzsch and Klipphausen in the Meißen district.

During World War II, a subcamp of Flossenbürg concentration camp was located here.