In Miami, Florida, fertility doctor Juliet Burke cares for her ill sister, Rachel Carlson (Robin Weigert), in a hospital where Ethan Rom (William Mapother) works.
Juliet is then interviewed by Richard Alpert (Nestor Carbonell) from a biomedical research company called Mittelos Bioscience, asking her to join their office in Portland, Oregon.
At the morgue to identify Edmund's body and sign the paperwork, Juliet cries and Ethan appears, handing her some tissues.
Juliet asks whether she can bring her sister, but Alpert admits it may be difficult for her to get her treatment at such a remote facility, as it is in fact "not quite in Portland."
Jack Shephard (Matthew Fox) holds Ben Linus (Michael Emerson) hostage in the operating room as Kate Austen (Evangeline Lilly) and James "Sawyer" Ford (Josh Holloway) escape.
Alex Rousseau (Tania Raymonde) helps them temporarily hide from their pursuers, and then reveals that she has a boat Kate and Sawyer may use to escape to the main island.
While Jack finishes Ben's operation with the help of Tom, Juliet kills Danny Pickett (Michael Bowen) as he finds the fugitives on the beach and is about to shoot Sawyer.
[4] IGN's Chris Carabott wrote that "if 'Not in Portland' didn't get you back on the Lost hype train then for goodness' sake the equally outstanding 'Flashes Before Your Eyes' hopefully grabbed your attention.