[8] It includes an audio mixer to set volume levels, perform panning, and add effects such as equalization, compression and reverb.

[9] From version 3 onward, it supports third-party VST effects and other third-party sound libraries, including presets for products from the Vienna Symphonic Library, EastWest, Miroslav Philharmonik, and Garritan Personal Orchestra.

[2] Notion's sample playback library was recorded at Abbey Road by the London Symphony Orchestra.

[2][10] The playback engine has options for real-time interpretation of tempi, articulations, and performance techniques.

[9] Starting with version 3.3 in 2016, the Studio One DAW (also developed by PreSonus) is integrated with Notion version 6 and above, allowing the two applications to perform real-time audio and MIDI streaming (via either ReWire or PreSonus' own UCNET protocol) to share audio, note, track, VST and score data, either with both applications running on the same computer, or on multiple computers connected to a network.