[3] This storied series began in 1909,[3][4] and there have been no more than two consecutive seasons without two teams meeting each other except from 1913 to 1929, 1938 to 1942, and 1979 to 1981.

Since 1982, the Panthers and Irish have remained a relative fixture on each other's schedules.

11 Notre Dame in South Bend, Indiana, en route to an undefeated season and a national championship.

[6] In 2012, Notre Dame's Everett Golson sparked a comeback from 14 points down in the fourth quarter to force overtime, and the Irish survived a narrowly-missed game-winning field goal attempt by the Panthers in the second OT, to pull out a 29–26 victory in triple OT at home to stay unbeaten en route to a perfect 12–0 regular season.

[7][8] The longest game in Notre Dame history occurred between the two schools in 2008, when Pitt defeated ND 36–33 in four overtimes at Notre Dame after the game was delayed briefly in the first overtime by the sprinklers in one end zone suddenly going off.