GNR trains originally used the Midland station in Nottingham, but there were frequent disputes, especially when the GNR began running through trains from London King's Cross via Grantham in a shorter time than the Midland Railway could manage.

When Nottingham Victoria railway station was opened in 1900, the Great Northern had to construct a new chord line, carried mainly on brick arches and steel girders, by means of a junction at Trent Lane, east of London Road, to Weekday Cross where it joined the Great Central main line.

The transfer to Victoria Station gave the Great Northern a prestigious location and avoided their need to reverse trains to and from Grantham, Derbyshire, and north of Nottingham.

[5] From 7 January 1963 passenger steam trains between Grantham, Bottesford, Elton and Orston, Aslockton, Bingham, Radcliffe-on-Trent, Netherfield and Colwick, Nottingham London-road (High Level) and Nottingham (Victoria) were replaced with diesel-multiple unit trains.

Although severely damaged by fire in 1996, the station building has been restored and was converted to a Holmes Place health and fitness club.