Nová Sedlica (Hungarian: Újszék; Rusyn: Новоселіця, Novosedlitsia; Ukrainian: Нова Седлиця, Nova sedlytsia) is the easternmost village and municipality in Slovakia (the easternmost point is the Mt.

Kremenec, the tripoint Slovakia-Ukraine-Poland is located at its summit), in Snina District in the Prešov Region.

Stužica, a component of the Primeval Beech Forests of the Carpathians UNESCO World Heritage Site is also close to the village.

Before the establishment of independent Czechoslovakia in 1918, Nová Sedlica was part of Zemplén County within the Kingdom of Hungary.

On 16 October 1944, the Red Army entered Nová Sedlica and it was once again part of Czechoslovakia.