Nové Mesto nad Váhom District (Slovak: okres Nové Mesto nad Váhom, Hungarian: Vágújhelyi járás) is a district in the Trenčín Region of western Slovakia.

Before 1920, the territory of the district was mostly part of the county of Kingdom of Hungary of Nyitra, with an area in the north forming part of the county of Trencsén.

The district has 32 municipalities.

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