Route 366 is a collector road in the Canadian province of Nova Scotia.

It is located in Cumberland County and connects East Amherst at Trunk 6 with Port Howe on Trunk 6.

At Tidnish Bridge the road connects to Route 970 at inter-provincial boundary with New Brunswick.

The entirety of the Collector Highway 366 was once designated as the Trunk Highway 66.

This Nova Scotia road, road transport or highway-related article is a stub.