[2] The first manmade nuclear explosion occurred on July 16, 1945, at 5:50 am on the Trinity test site near Alamogordo, New Mexico, in the United States, an area now known as the White Sands Missile Range.
RDS-1, dubbed "First Lightning" by the Soviets and "Joe-1" by the US, produced a 20 kiloton explosion and was essentially a copy of the American Fat Man plutonium implosion design.
[6] The United States' first thermonuclear weapon, Ivy Mike, was detonated on 1 November 1952 at Enewetak Atoll and yielded 10 Megatons of explosive force.
The first event occurred on the morning of 6 August 1945, when the United States Army Air Forces dropped a uranium gun-type device, code-named "Little Boy", on the city of Hiroshima, killing 70,000 people, including 20,000 Japanese combatants and 20,000 Korean slave laborers.
The second event occurred three days later when the United States Army Air Forces dropped a plutonium implosion-type device, code-named "Fat Man", on the city of Nagasaki.
A cloud of nuclear radiation travels from the hypocenter of the explosion, causing an impact to life forms even after the heat waves have ceased.
[11] Radiation exposure is delivered at the initial blast and can continue for an extended amount of time in the form of nuclear fallout.
The main health effect of nuclear fallout is cancer and birth defects because radiation causes changes in cells that can either kill or make them abnormal.
The idea became popularized in mainstream culture during the 1980s, when Richard P. Turco, Owen Toon, Thomas P. Ackerman, James B. Pollack and Carl Sagan collaborated and produced a scientific study which suggested the Earth's weather and climate can be severely impacted by nuclear war.
It's also assumed that fires will break out and become widespread, similar to what happened at Hiroshima and Nagasaki during the end of WWII, which will cause soot and other harmful particles to also be introduced into the atmosphere.
This is not unlike one of the leading theories about the extinction of most dinosaur species, in that a large explosion ejected small particulate matter into the atmosphere and resulted in a global catastrophe characterized by cooler temperatures, acid rain, and the KT Layer.