It is located beneath the Nuevos Ministerios (New Ministries) government complex and the AZCA financial centre at the junction of the Paseo de la Castellana and Joaquín Costa and Raimundo Fernández Villaverde streets in Madrid, Spain.

[4] The railway station currently used by Cercanías Madrid was inaugurated on 18 July 1967 as part of the original Atocha–Chamartín Rail Tunnel.

The Metro station opened twelve years later on 10 October 1979 when the first segment of Line 6 was inaugurated, running from Cuatro Caminos to Pacífico and including a stop at Nuevos Ministerios.

On 10 June 1982, a second set of platforms was added to the Metro station when the first segment of the old Line 8 was inaugurated, running from Fuencarral to Nuevos Ministerios.

Between 2002 and 2006, the station featured a service allowing passengers to check in for selected flights at Nuevos Ministerios and then board a train to the airport.