He is a member of the United Malays National Organisation (UMNO), a component party of the BN coalition.
On 12 May 2017, Nurulhisham was appointed as the Perlis State EXCO Member for the first term in charge of Public Facilities, Infrastructure, Rural Development, Poverty Eradication and Health by Menteri Besar Azlan to replace Jafperi Othman.
He won the seat and was elected into the Perlis State Legislative Assembly as the Simpang Empat MLA for the first term after narrowly defeating Rus'sele Eizan of Pakatan Rakyat (PR) by a majority of only 85 votes.
He defended the seat and was reelected as the Simpang Empat MLA for the second term after again narrowly defeating Rus'sele of Gagasan Sejahtera (GS) and Wan Noralhakim Shaghir Saad of Pakatan Harapan (PH) by a majority of only 82 votes.
He lost the seat and was not reelected as the Simpang Empat MLA after losing to Razali Saad of Perikatan Nasional (PN) by a minority of 4,008 votes.