Founded in 1946, it is located on a large estate in the town of Breukelen, between Amsterdam and Utrecht.

Nyenrode was founded under the name of the Netherlands Training Institute for Abroad (NOIB in Dutch) by renowned private Dutch companies, including KLM, Shell, Unilever, Philips, and AkzoNobel, with the objective 'For Business, By Business'.

The full-time and part-time MBA programs include a two-week module at Northwestern University's Kellogg School of Management near Chicago.

[2] In addition to Kellogg, Nyenrode has close connections with the University of Stellenbosch in South Africa,[3] the Vlerick Leuven Gent Management School in Belgium, the University of St. Gallen in Switzerland & S. P. Jain Institute of Management and Research in Mumbai.

In the Financial Times Ranking for European Business Schools (2020), Nyenrode was given an overall position of 41st.