She first appeared in Avengers: No Road Home #1 (April 2019) and was created by Al Ewing, Jim Zub, Mark Waid, and Paco Medina.
Due to her malevolent nature, Zeus imprisoned Nyx in such a manner that she would remain trapped until "the sun was parted from the earth," and hid the Night Shards within her soul in three secret places throughout the Universe.
She was then approached by Hercules, Scarlet Witch, Vision, Hulk, Hawkeye, Rocket Raccoon, Voyager, Monica Rambeau and eventually Conan.
Nyx retrieved her Shards of Night from Nightmare, Lord Librarian, and the Hyborian Age, but at the cost of her children's life.
Nyx decided to stay there and build worlds, cities, kingdoms, and temples full of people who are lovers, and poets.
She spared Hypnos so he can leave with Thor and Hercules to serve as her eyes and ears of the affairs of Gods and Heroes in the universe.