The name "One Two Three Airlines" refers to Chinese philosopher Laozi's three principles of Daoism.

[3] On 26 February 2020, China Eastern Airlines launched OTT Airlines as a subsidiary to operate Chinese-domestically produced aircraft, in addition to its existing business jet operations.

[5][6][7] In December 2020, the Civil Aviation Administration of China (CAAC) announced that it had completed a preliminary review of the airline's application for an operating license.

[7] Its launch plans included routes to Nanchang, Hefei, and Wenzhou starting in the first three months of 2021.

[8][9] The operation merge effected on September 22, 2024, marking the dissolution of the airline.