"O My Soul" is a song credited to Alex Chilton that was first released by Big Star on their 1974 album Radio City.

"[1][2] Bruce Eaton described the song as sounding like "the perfect set-opener for a killer live band", saying that "With its persistent stutter-stop skewed-soul guitar riff, garage rock Mellotron, explosive off-kilter drum fills, country-flavored guitar solo, and driving bass line, it serves loud notice that Radio City is not paint-by-numbers power pop.

"[1] AllMusic critic Mark Deming called "O My Soul" "a gloriously messy hodgepodge of slashed-out R&B rhythms, psychedelic chord twists, and smart pop melodicism" with a melody that "swerves all over the place.

"[3] Music journalist John M. Borack described the song as "strange but hooky" and praised Chilton's guitar playing.

"[6] The Commercial Appeal critic Walter Dawson considered it one of the "better cuts" on the album and particularly praised Jody Stephens' drumming.