[2] Odisha University of Health Sciences was established on 5 March 2023[3] to cater the much needed quality in medical education for the state of Odisha as an affiliating university ensuring affiliation, uniformity in various medical academic programmes, training and research in modern medicine, homeopathy, Ayurveda, Dental, Pharmacy, Nursing, Physiotherapy, Laboratory and Radiation Technology.

OUHS has started functioning from its temporary building at Sishu Bhawan Square, Bhubaneswar as per a notification issued by the Health and Family Welfare Department of Odisha on March 5, 2023 (Panchayati Raj and Lokaseva Divas).

In May 2023, Odisha State Cabinet chaired by CM Naveen Pattnaik approved ₹330.17 crore for the establishment of the university which will facilitate achieving excellence in the field of Medical and Allied Health Education and Research.

This university became active with the appointment of Dr. Datteswar Hota (former dean and principal of SCB Medical College and Hospital) as the first vice-chancellor of OUHS on 5 March 2023.

On 2024 institution signed multiple number of MoUs agreements with various national and international bodies to bring comprehensive improvement in the field of medical education, research.