Odododiodio is one of the constituencies represented in the Parliament of Ghana.

At the by-election held on the 30 August 2005, Jonathan Nii Tackie Komey (NDC) won with a majority of 8,377 to replace Samuel Nii Ayi Mankattah also of the NDC who had died earlier.

Mainly cosmopolitan constituency, Odododiodio’s diversity makes it a hotbed for politics.

It has been in existence since 1992 and covers communities in Ga Mashie, Ministries, Makola, Jamestown, Usher town and Kantamanto.

It shares boundaries with Klottey Korley, Ablekuma South and Dadetokopon.