Offinso South is one of the constituencies represented in the Parliament of Ghana.

It elects one Member of Parliament (MP) by the first past the post system of election.

Offinso South is located in the Offinso district of the Ashanti Region of Ghana.

The seat is located within the Offinso district of the Ashanti Region of Ghana.

At the by-election held on 24 October 2006, the New Patriotic Party (NPP) candidate, Owusu Achaw Duah, won the seat with a majority of 10,097.