The Ognon (French pronunciation: [ɔɲɔ̃] ⓘ) is a river of Eastern France.

It is a left tributary of the Saône, which it joins in Pontailler-sur-Saône.

Its source is in Haut-du-Them-Château-Lambert in the Vosges Mountains near the Ballon d'Alsace.

The Ognon flows through the following departments and towns: Haute-Saône, with Mélisey, Lure, Villersexel, Pesmes; Doubs, with Rougemont; Jura; Côte-d'Or, with Pontailler-sur-Saône.

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