Its studios and offices were co-located with sister station WBNS-TV, the CBS television affiliate for Columbus and central Ohio.

A special in-depth report on a topic of statewide interest is featured each Thursday night during Ohio's 9 o'clock news.

The show offers discussion of government in Ohio and Washington, D.C. Capitol Square regularly features the top newsmakers, who are questioned by moderator Jim Heath.

[7] To target younger viewers, the network airs The Brain Game each Thursday evening; the show features high school students in a quiz bowl setting.

Many Ohio High School Athletic Association events, including hockey, football, and basketball were aired on ONN.

ONN also aired weekly programming devoted to the Ohio State Buckeyes, Cincinnati Bearcats, and Miami Redhawks including live and tape delayed games.

ONN was one of the first TV networks to deliver live action sports video via Internet Protocol during the 2006-2007 school year for Miami Redhawks hockey.

ONN delivers the top statewide stories each day utilizing partnerships with news stations: WBNS in Columbus, WKBN in Youngstown, WEWS in Cleveland, WHIO in Dayton, WKRC in Cincinnati, WTOV in Steubenville/Wheeling, WTVG in Toledo, and WLIO in Lima.

ONN Radio provides statewide newscasts and sportscasts for affiliate stations during the day, anchored by staffers from WBNS-FM.