Its southern terminus is at SR 4 on the Huron–Seneca county line nearly seven miles (11 km) south of Bellevue, and its northern terminus is at the entrance to East Harbor State Park near Marblehead.

SR 269 was first designated in 1928 albeit on a much shorter route than it runs today.

The original two-mile-long (3.2 km) route served as a cutoff to the Sandusky Bay Bridge on SR 2 and SR 12 (modern-day U.S. Route 6).

[4][5] Two years later, SR 269 was extended much further south through Bellevue to its current southern terminus at SR 4.

[6][7] The route was extended north c. 1969 after SR 2 was moved onto the new Thomas Edison Bridge over the Sandusky Bay.