The dedication ceremony was held on May 18, 1940, when Bob Kepler (golf coach from 1938 to 1965), Chick Evans, Blanche Sohl, and Patty Berg played 18 holes on the Scarlet course.

In 2005 and 2006, the Scarlet Course underwent a major restoration project overseen by Jack Nicklaus that was intended to restore play on the Scarlet course to the way that MacKenzie had envisioned it.

In 1941, the first women's collegiate golf championship was played on the Scarlet course.

In 1982, Ohio State hosted the final Association for Intercollegiate Athletics for Women (AIAW) Division I National Championship.

The Scarlet Course has also played host to 10 men's National Championships.