The team kicked off the 2020 Myanmar National League with a 1–0 win over Rakhine United at Bago, claiming an instant fourth spot.

During this time, Hantharwady United won 13 games, drew 1 and lost 2, while scoring 42 goals and conceding only 12.

Due to the COVID-19 pandemic, General Aung San Shield was postponed, meaning Hantharwady United were guaranteed a spot in the play-off round of 2021 AFC Cup, which will be their first appearance in a continental competition.

To prepare for the upcoming 2021 Myanmar National League and 2021 AFC Cup, Hantharwady United have signed the veteran goalkeeper Pyae Phyo Aung from Southern Myanmar and Ye Yint Aung from Yadanarbon More signings will be made upon coach Myo Min Tun's decision over the transfer window.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.