OSU-Tulsa works in conjunction with the main OSU campus and Tulsa Community College to provide freshman and sophomore-level courses, enabling students to complete a four-year undergraduate course of study.

The Tulsa campus focuses on junior, senior and graduate level education, providing opportunities for individuals to complete bachelors, masters and doctoral degrees.

The campus is located north of downtown Tulsa, in the historic Greenwood neighborhood.

The Helmerich Advanced Technology Research Center (HATRC) is a recent campus addition.

This 125,000-square-foot (11,600 m2) engineering building is home to OSU's School of Materials Science and Engineering and has specialized labs for developing advanced materials targeted to local aerospace, biotechnology, and telecommunications, and manufacturing industries.