The Oklahoma State University System (OSU System) is a public university system in Oklahoma comprising five educational institutions: four general academic universities and one health sciences center.

The system's flagship institution is the Oklahoma State University campus in Stillwater.

As of Fall 2023, the OSU System is the largest university system in the state of Oklahoma with a total enrollment of 34,455 students.

[3] Two state agencies, OSU Ag Research and the Oklahoma Cooperative Extension Service, are also operated by the system and administered through Oklahoma State University–Stillwater.

This Oklahoma State-related article is a stub.