Built in the 1840s to serve a tiny college town community, it has experienced extensive alterations, but enough of its original qualities remain that it was named a historic site in the 1970s.

The community remained independent for approximately fifty years before being annexed into Cincinnati in pieces, beginning in 1911 and concluding in 1923.

Numerous civic institutions existed during College Hill's time as a separate village,[2]: 402  including a post office.

[2]: 402  It was not the first building to house postal operations in the community, as federal officials formally established the post office in September 1837 under the name of "Pleasant Hill, Ohio".

Two sections deviate from the basic plan: a rear addition that projects slightly to the side, and a two-story front porch with a door and balcony on the second floor.