The Greyhound Bus Station at 219 N. Lamar St., Jackson, Mississippi, was the site of many arrests during the May 1961 Freedom Rides of the Civil Rights Movement.

Incorporating a streamlined style and vertical, illuminated "Greyhound" marquee, it is unique for its structural glass exterior.

[2] Freedom Riders were civil rights activists who rode interstate buses into the segregated southern United States, in 1961 and subsequent years, to challenge the non-enforcement of the United States Supreme Court decisions which had ruled segregated public buses to be unconstitutional.

Upon arrival, riders would seek access to facilities denied to non-whites, such as waiting areas designated "Whites Only."

[3] Located within the southeast boundary of the Farish Street Neighborhood Historic District, the building was acquired by architect Robert Parker Adams in 1988; his firm restored the station's exterior and interior.