In March 1860, the school's name was changed to Louisiana State Seminary of Learning & Military Academy (le Lycee Scientifique et Militaire de l'Etat de la Louisiane).

After Louisiana seceded from the United States in January 1861, Sherman resigned as superintendent of the school.

In April 1861, large numbers of students and faculty began resigning in order to enlist in the Confederate military.

On November 1, 1869, the school was moved from Pineville and relocated to the capital city of Baton Rouge, Louisiana.

This article about a property in Louisiana on the National Register of Historic Places is a stub.