In 2015, he ran as a candidate for deputy to the National Assembly where he was the winner, later Prieto resigned his seat before starting the period in 2016 to remain in his initial position as mayor of San Francisco.

[6] Prieto affirmed that the opponents of Chavismo were no longer called "emaciated", but "traitors to the homeland," for supporting what, in his opinion, is an American military intervention.

[10] The government statement said "the sanctions hit high ranking officials of the Maduro regime, regional governors, and people directly implicated in activities undermining democratic institutions."

"[11] In 2021, Omar Prieto was put on the EU's sanctions list due to his active involvement in undermining and threatening Venezuela's democracy and rule of law in Zulia State as its governor and his support for the Maduro regime.

[12] Amazonas: Miguel Rodríguez Anzoátegui: Antonio Barreto Sira Apure: Ramón Carrizales Aragua: Daniela González Barinas: Argenis Chávez Bolívar: Justo Noguera Pietri Carabobo: Rafael Lacava Cojedes: Margaud Godoy Delta Amacuro: Lizeta Hernández Falcón: Víctor Clark Guárico: José Manuel Vásquez Lara: Adolfo Pereira Antique Mérida: Ramón Guevara Miranda: Héctor Rodríguez Monagas: Cosme Arzolay Nueva Esparta: Alfredo Díaz Portuguesa: Rafael Calles Sucre: Edwin Rojas Táchira: Laidy Gómez Trujillo: Henry Rangel Silva Vargas: José Manuel Suárez Yaracuy: Julio León Heredia Zulia: Omar Prieto Capital District: Jacqueline Faría (Head of Government) Territorio Insular Miranda: Félix Plasencia