[3] Her guests include the 14th Dalai Lama, Maya Angelou, Mohammed Fairouz, Desmond Tutu, Thich Nhat Hanh, Rosanne Cash, Wangari Maathai, Yo-Yo Ma, Paulo Coehlo, Brian Greene, John Polkinghorne, Jean Vanier, Joanna Macy, Sylvia Earle, and Elie Wiesel.

[5][10] As of July 2014, On Being aired on 334 public radio stations across the United States,[11] and the On Being podcast reached a global audience of 1.5 million listeners a month.

[14] The Columbia Journalism Review said of On Being and Tippett, "To listen to her show is to hear how intelligent and thoughtful religious people can be when they are allowed to be subjective and not merely regurgitate dogma.

"[15] In 2008 the show produced a series of programs called "Repossessing Virtue", exploring the spiritual and moral aspects of the economic recession.

"Science on Human Frontiers" included interviews with Brian Greene, Natalie Batalha, S. James Gates, Sylvia Earle, and Esther Sternberg.

Most recently On Being produced a special series on "The American Consciousness," a collection of live interviews at the Chautauqua Institution with Michel Martin, Richard Rodriguez, Imani Perry, and Nathan Schneider.

On the air and in print, Ms. Tippett avoids easy answers, embracing complexity and inviting people of every background to join her conversation about faith, ethics, and moral wisdom.