Zee starred or appeared in over 300 adult movies since entering the industry in 1986.

In 1990, she formed her own production company, Ona Zee Pictures.

[1] The company initially focused on bondage titles, but later moved on to other genres as well, such as feature and girl-girl movies.

[1][2] During the 1990s, she formed a pornographic performers' union, but it ultimately collapsed due to lack of political and legal support.

According to the TV series HBO Real Sex, Ona Zee was the spouse of Frank Zee, a Vietnam-era combat jet pilot.