Elton John One Night Only – The Greatest Hits is a live album released by English musician Elton John in 2000.

The album was recorded on 20 and 21 October 2000 at Madison Square Garden during his Medusa Tour.

An extended version was also released as a DVD, entitled One Night Only: The Greatest Hits Live at Madison Square Garden.

Due to technical issues on the first night, most of the recordings were drawn from the second show.

All compositions by Elton John and Bernie Taupin, except as indicated.