Upon her arrival to the airport, Lucas proposes to Peyton and the two fly to Vegas to elope; they quickly realize it isn't romantic enough, leading them to change their plans.

Mouth prepares to say goodbye to his friends, Tree Hill and Millicent, who plans to stay behind to help Brooke fight for her company against Victoria.

Dan survives being run over, but quickly realizes Carrie has taken him hostage to seek revenge on him for foiling her plans to kidnap Jamie.

Brooke is taking shooting lessons from Deb, meanwhile Quentin visits a gas station, entering into a fatal situation.

Brooke seeks help from a therapist and reveals she believes her mother hired someone to attack her before disclosing their difficult history.

Carrie breaks into the house to steal some of Jamie's things in advance of her plan to kidnap him and Brooke decides to confront Victoria directly, accusing her being behind the attack.

Nathan asks Deb to move back in and gives his blessing for her to be with Skills while Haley finds out Dan never answered the call for his new heart, wondering about his disappearance.

Sam and Brooke begin bonding, Mick drinks in a bar as he stares at a sobriety chip, and a dejected Peyton realizes he's not coming.

Millicent returns to Tree Hill, surprising Brooke with a list of things she always said she wanted to do that Victoria thought was stupid.

When Dan visits Tree Hill High, Nathan thanks him for saving Jamie and Haley but also reminds him they're standing in the same spot where he killed Keith.

Meanwhile, Lucas & Peyton lock themselves in their house together, obsessing over the magazine and engaging in a hilarious competition as Brooke vents to Haley about Sam stealing things from her and sneaking around.

Brooke, Haley, Peyton, Lucas, Millie, Jamie & Sam all watch Nathan partake in a violent game of SlamBall.

Millie starts to get jealous about Gigi working with Mouth while Lucas is offered to turn his first book into a movie by an LA producer named Julian Baker.

Brooke finds out Sam ran away with Jamie and broke into her store to throw a party where Peyton's wedding dress gets completely trashed.

Peyton remembers seeing Lindsey kiss Lucas at his book signing before running into Julian, who makes her laugh and takes her on a date.

Nathan encourages Haley to pursue her dreams and perform again while Brooke gets a call from the adoption agency, leading Sam to worry.

Sam works for Peyton at the USO concert for armed forces, expressing her fears about Brooke adopting a new child as Nathan imagines Q giving him grief about his failed comeback.

Gigi continues to hit on Mouth, ignoring his protests and Nate learns Q's death caused him to realize he's not invincible.

Brooke assures Sam she will always have a home with her as long as she wants to while Peyton feels guilty about Lucas not doing the movie because of her past with Julian.

Julian asks Peyton to get Lucas onboard with the movie because he believes in it and Nathan surprises Haley with a romantic gesture and she sings for him at home.

Brooke tells the adoption agency she's interested, but they're concerned about her fostering a teenager at the same time while Peyton encourages Lucas to continue with the movie adaption.

Nathan is a bartender who thinks he is a "nobody", Mouth is a journalist, Skills is a piano player, Brooke is desperate for money, and Peyton is being taken care of by Dan.

Haley prepares a reluctant Jamie for his school talent show, Nathan successfully changes his position to point guard in honor of Quentin's advice, and Lucas clashes with Julian's recommended movie director (guest star James Van Der Beek) over changing the script.

Brooke rejects Julian's earlier request while Mia refuses to sing songs written by other people, leading Peyton to suggest her to move to a different label.

Gigi continues pursuing Mouth, leading Millie to confront him before going to the bar to ease her pain with a drunk Owen.

As Brooke is leaving Jack's house, she realizes his brother is the one who attacked her and then fights to protect Sam before holding a gun to his head.

The episode closes with one of the most famous scenes in the series: at the hospital, a golden retriever devours the heart intended to be used for Dan's transplant.

Victoria returns to lure Brooke back to Clothes Over Bros. Haley and Nathan clash over the decision to pull Jamie from his school.

Skills keeps Jamie on a short leash, and Brooke does the same with Nick Lachey as she tries to make Julian jealous after he shows up with a date.

Lucas, Peyton and Sawyer pack up their stuff, and ride away in to the sunset with the newly repaired Comet, leaving Tree Hill for good as this season finale closes.