[2][3] The film stars Prithviraj Sukumaran, Anson Paul, Jayaprakash, Balachandra Menon, Pasupathy, Neeraj Madhav and Divya Pillai.

Oozham revolves around a demolition expert who teams up with his fiancée and brother to avenge the deaths of their family members from the corrupt scientist who got them killed.

While in a video chat with his sister Aishwarya and mother Subbalakshmi, Surya witness some goons murdering his whole family and is left devastated.

They checks a video in the account and learns that Krishnamoorthy and Parthasarathy were investigating about an epidemic outbreak in Tamil Nadu where they learn that Wilfred Marcus, the owner of a pharmaceutical company called Alpha Remedies is the mastermind behind Krishnamoorthy's and Parathasarthy's deaths as they were about to expose his involvement in spreading the outbreak and providing medicines for profits.

Marcus realizes that someone is tailing them and decide to hire "Captain" Anand Chathuranga, an ex-bomb squadron of the Sri Lankan Army who is now a freelancer and an explosive expert to protect them.

After completing Life of Josutty, director Jeethu Joseph announced his next film entitled Oozham which features Prithviraj Sukumaran in the lead.