Their descendants spread into various lines, Updegraff, Uptegraft, Updegraft, Updegrave, Updegrove, Uptegrove, Ubdegrove, Uptegraph, Upthagrove.

The Updegraff branch of Ohio belonged to the leading families of the Quaker religious movement and produced a long line of ministers and elders.

[11] The Op den Graeffs were originally Mennonites, and are believed to have come from nearby Aldekerk[12] in the Catholic Duchy of Julich about 1605 to avoid persecution.

At that time Krefeld was an exclave of the County of Moers, and under the authority of the Prince of Orange, stadtholder of the Republic of the United Netherlands.

They are among the thirteen families, the Original 13, the first closed group of German emigrants to North America, often referred to as the Germantown, Philadelphia, Pennsylvania Founders, who arrived on the ship Concord on October 6.

Some of them continued in or returned to the Mennonite faith and were found in the Montgomery County congregations of Skippack and Boyertown until modern times.

There is a reference about the Op den Graeff glass paintings of Krefeld, with a description of Herman's possible, but not proven, coat of arms, found in the estate of W. Niepoth (op den Graeff folder) in the archives of the city of Krefeld, who noted a letter dated November 17, 1935, from Richard Wolfferts to Dr Risler: "Saw the Coat of Arms glass pane in the old museum: 'Herman op den Graeff und Grietgen syn housfrau' or the like.

US-army captain William Hendry Upthegrove (* 1836) came to settle in the area near Gainesville in 1865 and founded a branch of the family in Florida.

[23][24] Updegrove line member: See also: The Op den Graeff family is sometimes said to be related to William Penn, the founder and gouverneur of Pennsylvania.